Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloro-amitriptyline → Amitriptyline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloro-amitriptyline | HCID 103696 | — |
| 반응물 | D-Tartaric acid | HCID 439655 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Amitriptyline | HCID 2160 | — |
반응 단계
1-Chloro-amitriptyline (196 mg) in 3 ml. absolute ethanol was added to an ethanolic solution of 1.1 eq. d-tartaric acid and warmed for 5-10 mins. The title compound was precipitated with ethyl ether as a white powder. After purity and identification checks, the overall yield from amitriptyline base was 32%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03991103 |
| 출처 데이터셋 | uspto-grants-1976_11 |
| ORD ID | ord-b196b6985ee74a0ebcf6527350330854 |
| 출처 메모 | uspto-grants-1976_11 |