Perillyl Alcohol → p-Menthan-7-ol

HRID 1730610노트

반응식

HRID 1730610 반응식
[C:1]([CH:4]1[CH2:9][CH2:8][C:7]([CH2:10][OH:11])=[CH:6][CH2:5]1)([CH3:3])=[CH2:2]>C(O)C.[Ni]>[CH:1]([CH:4]1[CH2:9][CH2:8][CH:7]([CH2:10][OH:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 10819Perillyl Alcohol

생성물 1

HCID 83763p-Menthan-7-ol

시약·촉매·용매 2

HCID 935Nickel촉매HCID 702Ethanol용매

실험 절차

10 g of 4-isopropenyl-cyclohex-1-enylmethanol dissolved in 200 ml of ethanol were hydrogenated at atmospheric pressure in the presence of 200 mg of Raney nickel. The reaction mixture was then filtered, evaporated and finally subjected to a fractional distillation. It was thus isolated a product having bp 75° - 115°/10 Torr. The vapour phase chromatography analysis showed that the isolated product contained 50% of a 60 : 40 (parts by weight) mixture of cis and trans isomers of the desired alcohol.

후처리

  1. filtrationThe reaction mixture was then filtered
  2. customevaporated
  3. distillationfinally subjected to a fractional distillation
  4. customIt was thus isolated a product

출처 및 근거

ORD 기록
ord-c95d78e86b2242ffb298fb7752c52229
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03993604

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