2-Amino-4-methylpyridine → HCID 20228720, 화합물

반응식

Br[CH:2]([CH3:16])[C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]=2[CH:15]=1)=O.[NH2:17][C:18]1[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][N:19]=1>>[CH3:16][C:2]1[N:19]2[CH:20]=[CH:21][C:22]([CH3:24])=[CH:23][C:18]2=[N:17][C:3]=1[C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]=2[CH:15]=1

참가 물질

반응물 2

HCID 15332-Amino-4-methylpyridine

HCID 202287165-(2-Bromopropanoyl)-3-methyl-1,3-benzoxazol-2(3H)-one

생성물 1

HCID 20228720HCID 20228720, 화합물수율 46%

실험 절차

5-(3,7-Dimethylimidazo[1,2-a]pyridin-2-yl)-3-methyl-2-benzoxazolinone (1.35 g) was prepared in the substantially same manner as that of Example 4 from 5-(2-bromopropionyl)-3-methyl-2-benzoxazolinone (2.84 g) and 2-amino-4-methylpyridine (3.24 g).

출처 및 근거

ORD 기록: ord-2aa9527bef174457b0d9300f032408b9
출처 데이터셋: uspto-grants-1986_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04621084

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