2-Amino-4-methylpyridine (HCID 1533)

이름 및 식별자

우선 이름: 2-Amino-4-methylpyridine
IUPAC: 4-methylpyridin-2-amine
영어명: 4-Methylpyridin-2-amine
분자식: C6H8N2
분자량: 108.14

이름 및 동의어

2-amino-4-methylpyridine4-METHYLPYRIDIN-2-AMINE695-34-12-Amino-4-picolineAminopicolineAscensil2-Pyridinamine, 4-methyl-4-Methyl-2-pyridinamine4-Methyl-2-aminopyridine4-Methyl-2-pyridylamine4-PICOLINE, 2-AMINO-RA 1226

이름 더 보기

Rifaximin EP Impurity Aw45W 454M2APra1226NSC 1490

VMI 20-4DTXSID1044720NSC-1490NSC-6972394N1Z644HRA-1226DTXCID9024720NSC-176165

데이터베이스 식별자

CAS: 695-34-1
PubChem CID: 1533
DTXSID: DTXSID1044720
ChEMBL: CHEMBL40833
UNII: 394N1Z644H
EC Number: 211-780-9
Nikkaji: J31.382C

물성

구조 계산 물성

XLogP: 0.6
극성 표면적: 38.9 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 72

실험 및 물리화학적 성질

Kovats Retention Index · 3건

1153

1113

1952；2001

Collision Cross Section118.1 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID1044720]；119.5 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID1044720]

물리화학적 성질

녹는점: 96 · 96-99 °C (lit.)
끓는 점: 230 °C · 230 °C (lit.)
밀도: 1.0275 · 1.0275 (estimate)
증기압: 3.71 Pa · 3.71Pa at 25℃
굴절률: 1.556 · 1.5560 (estimate)
인화점: 118 °C · 118 °C
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
용해도: DMF: 자유롭게 용해됨
물리적 상태: 플레이크
산도 계수 (pKa): 1 · pK1: 7.48(+1) (25°C)
색상: 약간 노란색에서 베이지색 또는 갈색
수용성: 녹는
Merck: 14 · 14,466
BRN: 107066 · 107066
InChI: 1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
InChIKey: ORLGLBZRQYOWNA-UHFFFAOYSA-N
SMILES: Cc1ccnc(N)c1
LogP: 0.56 · 0.56-1.08
NIST: 2 · 2-Pyridinamine, 4-methyl-(695-34-1)
EPA: 2 · 2-Pyridinamine, 4-methyl- (695-34-1)

화학적 성질

Light yellow to brown flakes

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 0.8% (1 of 122) of reports.

Danger

H301 (99.2%): Toxic if swallowed [Danger Acute toxicity, oral]；H311 (47.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (64.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (61.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H331 (32.8%): Toxic if inhaled [Danger Acute toxicity, inhalation]；H335 (64.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H373 (32.8%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 122 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 122 reports by companies.；There are 14 notifications provided by 121 of 122 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 07-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/20101

2-Amino-4-methylpyridine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 3 (99.2%)；Acute Tox. 3 (47.5%)；Skin Irrit. 2 (64.8%)；Eye Irrit. 2 (61.5%)；Acute Tox. 3 (32.8%)；STOT SE 3 (64.8%)；STOT RE 2 (32.8%)

규제 정보

Regulatory Information · 2건

Status: Active Update: 07-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/20101

2-Amino-4-methylpyridine: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: TJ5150000
ridadr: UN 3086 6.1/PG 1
독성: LD50 oral in rat: 200mg/kg
HS 번호: 29333999
risk_code: 45-46-60-61-8-21-25-26-34-42/43-48/23-50/53-36/37/38-33-23/24/25
hazard_code: T
safety_code: 53-45-60-61-37/39-28A-26-36/37/39
포장분류: II
위험 등급: 6.1
Hazard Classifications: Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralAquatic Chronic 3Eye Dam. 1Skin Corr. 1B
스토리지 클래스: 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials

화학 및 산업

용도 및 제조

General Manufacturing Information2-Pyridinamine, 4-methyl-: ACTIVE

응용 분야

용도Intermediate, medicine.

일반 설명4-Methylpyridin-2-amine acts as ligand and forms methoxo-bridged copper(II) complexes.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

연결된 노트

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2-Amino-4-methylpyridine

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