2-Amino-5-methylpyridine → HCID 20228722, 화합물

반응식

Br[CH:2]([CH3:16])[C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]=2[CH:15]=1)=O.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][N:19]=1>>[CH3:16][C:2]1[N:19]2[CH:20]=[C:21]([CH3:24])[CH:22]=[CH:23][C:18]2=[N:17][C:3]=1[C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]=2[CH:15]=1

참가 물질

반응물 2

HCID 153482-Amino-5-methylpyridine

HCID 202287165-(2-Bromopropanoyl)-3-methyl-1,3-benzoxazol-2(3H)-one

생성물 1

HCID 20228722HCID 20228722, 화합물수율 77.9%

실험 절차

5-(3,6-Dimethylimidazo[1,2-a]pyridin-2-yl)-3-methyl-2-benzoxazolinone (1.85 g) was prepared in substantially the same manner as that of Example 30 from 5-(2-bromopropionyl)-3-methyl-2-benzoxazolinone (2.3 g) and 2-amino-5-methylpyridine (2.6 g). mp. 247°-249° C.

출처 및 근거

ORD 기록: ord-4f177dcfb5a443a9bff0b21d14699ce2
출처 데이터셋: uspto-grants-1986_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04621084

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