Hydrochloric Acid → HCID 19739392, 화합물

HRID 1731455노트

반응식

HRID 1731455 반응식
C1CO[CH:3]([CH2:4][CH2:5][CH2:6][C:7]2[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=2)[O:2]1.O1CCCC1.Cl>O>[C:11]([C:10]1[CH:13]=[CH:14][C:7]([CH2:6][CH2:5][CH2:4][CH:3]=[O:2])=[CH:8][CH:9]=1)#[N:12]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 10856924HCID 10856924, 화합물

생성물 1

HCID 19739392HCID 19739392, 화합물수율 116.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 2.8 g of p-(4,4-ethylenedioxybutyl)benzonitrile, 56 ml of tetrahydrofuran and 56 ml of 10% hydrochloric acid was stirred for 3 hours at room temperature and then left to stand overnight. Thereafter, the reaction mixture was diluted with water and extracted three times with diethyl ether. The organic phases were washed twice with water, dried over magnesium sulphate, filtered and concentrated. There were obtained 2.6 g of 4-(p-cyanophenyl)butyraldehyde which was processed without additional purification.

후처리

  1. waitleft
  2. waitto stand overnight
  3. extractionextracted three times with diethyl ether
  4. washThe organic phases were washed twice with water
  5. dry with materialdried over magnesium sulphate
  6. filtrationfiltered
  7. concentrationconcentrated

출처 및 근거

ORD 기록
ord-65f78fed37314ea4b5037e2422b3b91c
출처 데이터셋
uspto-grants-1986_11
특허 번호
US04621901

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