Sodium Hydroxide → 4-Carbamoyl-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-2-acetic acid

HRID 1732851노트

반응식

HRID 1732851 반응식
[C:1]([C:4]1([CH3:22])[C:11]2[C:7](=[C:8]([CH3:19])[N:9]([CH2:13][C:14]([O:16]CC)=[O:15])[C:10]=2[CH3:12])[C:6]([CH3:21])([CH3:20])[CH2:5]1)(=[O:3])[NH2:2].[OH-].[Na+]>>[C:1]([C:4]1([CH3:22])[C:11]2[C:7](=[C:8]([CH3:19])[N:9]([CH2:13][C:14]([OH:16])=[O:15])[C:10]=2[CH3:12])[C:6]([CH3:21])([CH3:20])[CH2:5]1)(=[O:3])[NH2:2]

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 12894334Ethyl 4-carbamoyl-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-2-acetate

생성물 1

HCID 234562094-Carbamoyl-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-2-acetic acid

실험 절차

Reaction of the ethyl 4-carbamoyl-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-2-acetate described above in Example 20AC with alcoholic sodium hydroxide and isolation of the product from an acid or neutral medium affords 4-carbamoyl-2,4,5,6-tetrahydro-1,3,4,6,6-pentamethylcyclopenta[c]pyrrole-2-acetic acid.

출처 및 근거

ORD 기록
ord-9e8d9580e0c541438dc3690dbd2bbf85
출처 데이터셋
uspto-grants-1980_12
특허 번호
US04239687

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