Potassium Hydroxide → HCID 9873033, 화합물
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C[O:2][C:3]([C:5]1[CH:43]=[CH:42][C:8]([O:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[C:36]([CH3:37])=[C:35]([CH3:38])[C:17]([C:18]([O:20][C:21]3[C:29]([CH3:30])=[C:28]([CH3:31])[C:24]([C:25]([NH2:27])=[O:26])=[C:23]([O:32][CH3:33])[C:22]=3[CH3:34])=[O:19])=[C:16]([O:39][CH3:40])[C:15]=2[CH3:41])=[CH:7][CH:6]=1)=[O:4].[OH-].[K+]>CS(C)=O>[C:3]([C:5]1[CH:6]=[CH:7][C:8]([O:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[C:36]([CH3:37])=[C:35]([CH3:38])[C:17]([C:18]([O:20][C:21]3[C:29]([CH3:30])=[C:28]([CH3:31])[C:24]([C:25]([NH2:27])=[O:26])=[C:23]([O:32][CH3:33])[C:22]=3[CH3:34])=[O:19])=[C:16]([O:39][CH3:40])[C:15]=2[CH3:41])=[CH:42][CH:43]=1)([OH:4])=[O:2]참가 물질
4
실험 절차
To a solution of the amide-ester prepared in Example 46 (101, 694 mg, 1.17 mmol) in 30 ml of DMSO, was added 1N-KOH (3.5 ml, 3.5 mmol) with stirring, so that the amide-ester was subjected to hydrolysis to give 602 mg of the title compound 102 (89%).