Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 6-(Bromomethyl)-2,4-diaminopyrido [2,3-d]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 2,4-Diamino-6-(hydroxymethyl)pyrido[2,3-d]pyrimidine | HCID 487416 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 6-(Bromomethyl)-2,4-diaminopyrido [2,3-d]pyrimidine | HCID 10562861 | — |
반응 단계
The intermediate III-2 was prepared from 2,4-diaminopyrido [2,3-d]pyrimidine-6-methanol (III-1) by the procedure described in J. Med. Chem., 35:332 (1992). This particular preparation analyzed for a 1.75 HBr° 0.25 CH3COOH salt (formula wt. 406.7). The material was suitable for conversions to compound 33.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05536724 |
| 출처 데이터셋 | uspto-grants-1996_07 |
| ORD ID | ord-4519af7ad0c042d9b7c1e74387c6d76a |
| 출처 메모 | uspto-grants-1996_07 |