Potassium thiocyanate → 3-Methyl-4-thiocyanato-5-aminoisothiazole

HRID 1735689노트

반응식

HRID 1735689 반응식
[CH3:1][C:2]1[C:6](Br)=[C:5]([NH2:8])[S:4][N:3]=1.[C:9]([S-:11])#[N:10].[K+]>CO>[CH3:1][C:2]1[C:6]([S:11][C:9]#[N:10])=[C:5]([NH2:8])[S:4][N:3]=1

참가 물질

4

반응물 2

HCID 516872Potassium thiocyanateHCID 177499314-Bromo-3-methyl-1,2-thiazol-5-amine

생성물 1

HCID 146188853-Methyl-4-thiocyanato-5-aminoisothiazole

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

386 g of 3-methyl-4-bromo-5-aminoisothiazole and 200 g of KSCN in methanol are refluxed for 6 hours. The product crystallizes out on cooling. 800 ml of water are added and the product is filtered off under suction and washed with water.

후처리

  1. customThe product crystallizes out
  2. temperatureon cooling
  3. addition800 ml of water are added
  4. filtrationthe product is filtered off under suction
  5. washwashed with water

출처 및 근거

ORD 기록
ord-7f6a56f2abef48c7b73daed48f3895b6
출처 데이터셋
uspto-grants-1996_07
특허 번호
US05538939

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