Methyl iodide → 5-Butyl-2-triethylsilyl-4-furaldehyde

HRID 1736520

반응식

HRID 1736520 반응식
[CH3:1][C:2]1OC([Si](C)(C)C)=[CH:4][C:3]=1C=O.CI.[CH2:15]([Si:17]([CH2:27][CH3:28])([CH2:25][CH3:26])[C:18]1[O:19][CH:20]=[C:21]([CH:23]=[O:24])[CH:22]=1)[CH3:16].ICCCC>>[CH2:1]([C:20]1[O:19][C:18]([Si:17]([CH2:25][CH3:26])([CH2:15][CH3:16])[CH2:27][CH3:28])=[CH:22][C:21]=1[CH:23]=[O:24])[CH2:2][CH2:3][CH3:4]

참가 물질

5

반응물 4

HCID 6328Methyl iodideHCID 10962Butyl iodideHCID 108784383-Furancarboxaldehyde, 5-(triethylsilyl)-HCID 157445905Methyl-2-trimethylsilyl-4-furaldehyde

생성물 1

HCID 150371455-Butyl-2-triethylsilyl-4-furaldehyde

실험 절차

Using the same procedure as for 5-methyl-2-trimethylsilyl-4-furaldehyde but substituting 2-trimethylsilyl-4-furaldehyde and methyl iodide with 2-triethylsilyl-4-furaldehyde and 1-iodobutane, respectively, gives 5-butyl-2-triethylsilyl-4-furaldehyde. IR (neat) 1690 cm-1; 'HNMR (CDCl3) 0.73 (q, 6H, J=8.4 Hz), 0.95 (m, 12H), 1.36 (p, 2H, J=7.5 Hz), 1.69 (p, 2H, J=7.5 Hz), 2.94 (t, 2H, J=7.5 Hz), 6.89 (s, 1H) and 9.91 (s, 1H) 13CNMR (CDCl3): 3.03, 7.17, 13.6, 22.2, 26.8, 30.4, 118.6, 122.5 158.4, 170.2 and 184.8. LRMS m/e (% abundance) 266 (M+, 20) 238 (20) 237 (100), 87 (10) and 75 (20); HRMS exact mass calculated for C15H26O2Si 266.1702, found 266.1690.

출처 및 근거

ORD 기록
ord-968a803ba61c4c228630490efb6caa7b
출처 데이터셋
uspto-grants-1996_07
특허 번호
US05541221

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