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Phenyl Isothiocyanate → 6-Nitro2,3-dioxo-1,2,3,4,7,10-hexahydro-8H-pyrido[3,4-f]quinoxaline-9-carbothioic Acid Phenylamide

HRID 1739675
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인쇄 미리보기

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HRID 1739675 반응식
[N+:1]([C:4]1[C:13]2[N:14]=[CH:15][CH:16]=[CH:17][C:12]=2[C:11]2[C:6](=[N:7][C:8](=[O:19])[C:9](=[O:18])[N:10]=2)[CH:5]=1)([O-:3])=[O:2].[C:20]1([N:26]=[C:27]=[S:28])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C(N(CC)CC)C>CN(C=O)C>[C:20]1([NH:26][C:27]([N:14]2[CH2:15][CH2:16][C:17]3[C:4]([N+:1]([O-:3])=[O:2])=[CH:5][C:6]4[NH:7][C:8](=[O:19])[C:9](=[O:18])[NH:10][C:11]=4[C:12]=3[CH2:13]2)=[S:28])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1
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참가 물질

5

반응물 3

HCID 7673Phenyl IsothiocyanateHCID 8471TriethylamineHCID 727442526-Nitropyridoquinoxalinedione

생성물 1

HCID 154347146-Nitro2,3-dioxo-1,2,3,4,7,10-hexahydro-8H-pyrido[3,4-f]quinoxaline-9-carbothioic Acid Phenylamide

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
60 °C

실험 절차

A mixture of the 6-nitropyridoquinoxalinedione (0.1 g, 0.38 mmol), phenylisothiocyanate (70 μL), triethylamine (70 μL) in DMF (5 mL) was stirred at 60° C. for 24 hours. The mixture was poured onto water and allowed to stand. The precipitate was collected by filtration, washed with water and ether, and dried in vacuo to give product (130 mg) as a beige solid; mp 270-274° C., nmR, IR.

후처리

  1. additionThe mixture was poured onto water
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with water and ether
  4. customdried in vacuo

출처 및 근거

ORD 기록
ord-14f3f6e8517d4040b4b7d4ed5cd21ce1
출처 데이터셋
uspto-grants-1999_10
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05968928

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