Nitroethane → HCID 73877165, 화합물

HRID 1743383노트

반응식

HRID 1743383 반응식
[CH3:1][O:2][C:3]1[C:10]([CH3:11])=[C:9]([CH3:12])[C:8]([O:13][CH3:14])=[CH:7][C:4]=1[CH:5]=O.C([O-])(=O)C.[NH4+].[N+:20]([CH2:23][CH3:24])([O-:22])=[O:21]>C(OC(C)C)(C)C>[CH3:14][O:13][C:8]1[CH:7]=[C:4]([CH:5]=[C:23]([N+:20]([O-:22])=[O:21])[CH3:24])[C:3]([O:2][CH3:1])=[C:10]([CH3:11])[C:9]=1[CH3:12]

참가 물질

5

반응물 3

HCID 6587NitroethaneHCID 517165Ammonium AcetateHCID 12629035HCID 12629035, 화합물

생성물 1

HCID 73877165HCID 73877165, 화합물수율 67%

시약·촉매·용매 1

HCID 7914Diisopropyl Ether용매

실험 절차

A mixture of 2,5-dimethoxy-3,4-dimethylbenzaldehyde (38.9 g, 0.20 mol), ammonium acetate (10 g, 0.13 mol) and nitroethane (200 mL) was heated to reflux for 2 hours. The reaction mixture was diluted with diisopropyl ether, washed with water and saturated brine, dried over magnesium sulfate, filtered and concentrated under reduced pressure. The residue was recrystallized from hexane to obtain 33.6 g of the title compound.

후처리

  1. temperaturewas heated
  2. temperatureto reflux for 2 hours
  3. washwashed with water and saturated brine
  4. dry with materialdried over magnesium sulfate
  5. filtrationfiltered
  6. concentrationconcentrated under reduced pressure
  7. customThe residue was recrystallized from hexane

출처 및 근거

ORD 기록
ord-3f15c87921b147b5a1ee387f0a6eda2b
출처 데이터셋
uspto-grants-2006_03
특허 번호
US07008940B1

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