Acetic Anhydride → HCID 22238064, 화합물

HRID 1743385노트

반응식

HRID 1743385 반응식
[C:1](OC(=O)C)(=[O:3])C.[CH3:8][CH:9]1[CH2:17][C:16]2[C:11](=[C:12]([CH3:20])[C:13]([CH3:19])=[C:14]([OH:18])[CH:15]=2)[NH:10]1>C(O)=O>[OH:18][C:14]1[CH:15]=[C:16]2[C:11](=[C:12]([CH3:20])[C:13]=1[CH3:19])[N:10]([CH:1]=[O:3])[CH:9]([CH3:8])[CH2:17]2

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 22238098HCID 22238098, 화합물

생성물 1

HCID 22238064HCID 22238064, 화합물수율 49%

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

Acetic anhydride (0.76 mL, 8.1 mmol) was added to formic acid (4 mL), and the mixture was stirred at room temperature for 15 minutes. To this solution was added 2,3-dihydro-2,6,7-trimethyl-1H-indole-5-ol (0.71 g, 4.0 mmol), and the mixture was stirred at room temperature for 5 hours. Ice was added to the reaction mixture, and precipitated solid was filtered to obtain 0.40 g of the title compound.

후처리

  1. stirringthe mixture was stirred at room temperature for 5 hours
  2. additionIce was added to the reaction mixture
  3. customprecipitated solid
  4. filtrationwas filtered

출처 및 근거

ORD 기록
ord-bbaa5d85196d44da98a1b9ee0d7f8902
출처 데이터셋
uspto-grants-2006_03
특허 번호
US07008940B1

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