Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrile → N-[2-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrile | HCID 22227997 | — |
| 반응물 | 5-Methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride | HCID 22228086 | — |
| 생성물 | N-[2-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide | HCID 22228003 | 39.9% |
반응 단계
By the reaction and treatment in the same manner as in Example 150 using 5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride (0.9 g) and 2-amino-5-(4-morpholinopiperidin-1-yl)benzonitrile (0.9 g), the title compound (0.67 g) was obtained, melting point: 210–212° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07015218B1 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-3d247a9990724c99899a54fd267f7176 |
| 출처 메모 | uspto-grants-2006_03 |