Diisopropylethylamine → methyl (2S,3R)-3-(difluoromethoxy)-1-oxo-1-((S)-2-(5-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)butan-2-ylcarbamate

반응식

[F:1][CH:2]([F:15])[O:3][C@H:4]([CH3:14])[C@H:5]([NH:9][C:10]([O:12][CH3:13])=[O:11])[C:6]([OH:8])=O.[NH:16]1[CH2:20][CH2:19][CH2:18][C@H:17]1[C:21]1[NH:22][C:23]([C:26]2[CH:35]=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[C:31]([B:36]4[O:40][C:39]([CH3:42])([CH3:41])[C:38]([CH3:44])([CH3:43])[O:37]4)[CH:32]=3)[CH:27]=2)=[CH:24][N:25]=1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.C(N(C(C)C)CC)(C)C>CN(C)C=O.C(OCC)(=O)C>[F:15][CH:2]([F:1])[O:3][C@H:4]([CH3:14])[C@H:5]([NH:9][C:10](=[O:11])[O:12][CH3:13])[C:6](=[O:8])[N:16]1[CH2:20][CH2:19][CH2:18][C@H:17]1[C:21]1[NH:22][C:23]([C:26]2[CH:35]=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[C:31]([B:36]4[O:40][C:39]([CH3:42])([CH3:41])[C:38]([CH3:44])([CH3:43])[O:37]4)[CH:32]=3)[CH:27]=2)=[CH:24][N:25]=1