Hydrochloric Acid → 2-[5-(2,2-Dimethylpropoxy)pyridin-2-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one hydrochloride

HRID 1753834노트

반응식

HRID 1753834 반응식
[ClH:1].[CH3:2][C:3]([CH3:24])([CH3:23])[CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]([N:12]2[C:16](=[O:17])[C:15]([N:18]3[CH:22]=[CH:21][N:20]=[N:19]3)=[CH:14][NH:13]2)=[N:10][CH:11]=1>O1CCOCC1>[ClH:1].[CH3:2][C:3]([CH3:24])([CH3:23])[CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]([N:12]2[C:16](=[O:17])[C:15]([N:18]3[CH:22]=[CH:21][N:20]=[N:19]3)=[CH:14][NH:13]2)=[N:10][CH:11]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 596035532-[5-(2,2-Dimethylpropoxy)pyridin-2-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one

생성물 1

HCID 674577372-[5-(2,2-Dimethylpropoxy)pyridin-2-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one hydrochloride

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

2 ml of a 4 N solution of hydrogen chloride in dioxane are added to 22 mg (0.1 mmol) of the compound from Example 84 and the mixture is stirred at RT for 1 h. The solid is filtered off and dried under a high vacuum.

후처리

  1. filtrationThe solid is filtered off
  2. customdried under a high vacuum

출처 및 근거

ORD 기록
ord-788e0e6e21724637b09312509a78f4bd
출처 데이터셋
uspto-grants-2015_10
특허 번호
US09168249B2

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