Thiourea → HCID 178429715, 화합물
반응식
[N:1]([CH2:4][C:5]1[N:15]=[C:8]2[N:9]=[C:10]([CH3:14])[CH:11]=[C:12](Cl)[N:7]2[N:6]=1)=[N+:2]=[N-:3].NC(N)=[S:18]>C(O)C>[N:1]([CH2:4][C:5]1[N:15]=[C:8]2[N:9]=[C:10]([CH3:14])[CH:11]=[C:12]([SH:18])[N:7]2[N:6]=1)=[N+:2]=[N-:3]참가 물질
4
실험 절차
2-Azidomethyl-7-chloro-5-methyl[1.2.4]triazolo-[1,5-a]pyrimidine (2.98 g) are suspended in 70 ml of ethanol, treated with 1.1 g of thiourea and heated at reflux for 45 minutes. The reaction mixture is stirred in an ice bath for 30 minutes. The resulting precipitate is filtered off under suction and dried in a vacuum at 40° C. There are obtained 2.76 g of 2-azidomethyl-5methyl[1.2.4]triazolo[1,5-a]pyrimidine-7-thiol as yellow crystals of melting point 214°-215° C.
후처리
- temperatureheated
- temperatureat reflux for 45 minutes
- filtrationThe resulting precipitate is filtered off under suction
- customdried in a vacuum at 40° C
출처 및 근거
- ORD 기록
- ord-937c5193da354e5da954000b19cd3d47
- 출처 데이터셋
- uspto-grants-1995_08
- 특허 번호
- US05438052
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