Hydrochloric Acid → 2-Amino-1-[3-(5-amino-1-methyl-4-pyrazolyl)phenyl]benzimidazole hydrochloride

반응식

[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:13]3[CH:14]=[N:15][N:16]([CH3:22])[C:17]=3[NH:18]C(=O)C)[CH:8]=2)[C:5]2[CH:23]=[CH:24][CH:25]=[CH:26][C:4]=2[N:3]=1.[ClH:27]>>[ClH:27].[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:13]3[CH:14]=[N:15][N:16]([CH3:22])[C:17]=3[NH2:18])[CH:8]=2)[C:5]2[CH:23]=[CH:24][CH:25]=[CH:26][C:4]=2[N:3]=1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 19390940HCID 19390940, 화합물

생성물 1

HCID 193909582-Amino-1-[3-(5-amino-1-methyl-4-pyrazolyl)phenyl]benzimidazole hydrochloride

실험 절차

2-Amino-1-[3-(5-amino-1-methyl-4-pyrazolyl)phenyl]benzimidazole hydrochloride was prepared from 2-amino-1-[3-(5-acetamido-1-methyl-4-pyrazolyl)phenyl]benzimidazole by hydrolysis with 25% refluxing hydrochloric acid. mp 190°-193° C.

출처 및 근거

ORD 기록: ord-9865151cf8f04bf0a8cc6a3b80230cf7
출처 데이터셋: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05441969

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