Water → HCID 178443206, 화합물

HRID 1756990노트

반응식

HRID 1756990 반응식
Cl.[NH2:2][OH:3].C(N(CC)CC)C.[C:11](#[N:24])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].O>C(O)C.O.C(O)C>[OH:3][NH:2][C:11](=[NH:24])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

참가 물질

7

반응물 4

HCID 962WaterHCID 8471TriethylamineHCID 12390TridecanenitrileHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 178443206HCID 178443206, 화합물수율 26.5%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 19096565Water ethanol용매

실험 절차

Hydroxylamine hydrochloride (0.90 g, 12.9 mmol) was added to a solution of triethylamine (1.79 mL, 12.9 mmol) in 50% ethanol/water (4 mL) and the mixture was stirred for 2 minutes. Tridecane nitrile (2.02 g, 10.4 mmol) in ethanol (10 mL) was added and the mixture refluxed for 2 hours, allowed to cool, and poured into water (50 mL). The precipitate was collected, stirred with hexanes, and filtered to yield a white solid (0.63 g, 26%).

후처리

  1. temperaturethe mixture refluxed for 2 hours
  2. temperatureto cool
  3. customThe precipitate was collected
  4. stirringstirred with hexanes
  5. filtrationfiltered

출처 및 근거

ORD 기록
ord-571455ffa192480696a3ed86f3b5ed48
출처 데이터셋
uspto-grants-1995_08
특허 번호
US05441975

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