Methyl 4-bromobenzoate → 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester

HRID 1757486

반응식

HRID 1757486 반응식
[CH3:1][C:2]([N:10]1[N:14]=[N:13][C:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[N:11]1)([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:3].Br[C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=1>[Ni]>[CH3:29][O:28][C:26]([C:25]1[CH:30]=[CH:31][C:22]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:12]2[N:13]=[N:14][N:10]([C:2]([CH3:1])([C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH3:3])[N:11]=2)=[CH:23][CH:24]=1)=[O:27]

참가 물질

4

반응물 2

HCID 12081Methyl 4-bromobenzoateHCID 12895945-phenyl-2-(2-phenylpropan-2-yl)-2H-tetrazole

생성물 1

HCID 118254832'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

reacting the ortho-transmetalated 2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole with methyl 4-bromobenzoate in the presence of phospinated nickel catalyst to give 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester,

출처 및 근거

ORD 기록
ord-51d3767627e343328905b27d86cdf506
출처 데이터셋
uspto-grants-1995_08
특허 번호
US05446121

연결된 노트

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