Benzoyl chloride → 3-Chloro-2,2,3-trifluoro-propionyl chloride

HRID 1759583노트

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HRID 1759583 반응식
[Cl:1][CH:2]([F:9])[C:3]([F:8])([F:7])[C:4](O)=[O:5].C([Cl:18])(=O)C1C=CC=CC=1>>[Cl:1][CH:2]([F:9])[C:3]([F:8])([F:7])[C:4]([Cl:18])=[O:5]

참가 물질

3

반응물 2

HCID 7412Benzoyl chlorideHCID 205313223-Chloro-2,2,3-trifluoropropanoic acid

생성물 1

HCID 141224163-Chloro-2,2,3-trifluoro-propionyl chloride

실험 절차

In a three-necked 2 l flask provided with a Vigreux column, a condenser, and a collecting flask were brought 325 g (2 moles) of 3-chloro-2,2,3-trifluoro-propionic acid (Org.Synth.Coll. 5, 239) and 562 g (4 moles) of benzoyl chloride. The mixture was heated so that the acid chloride distilled over slowly. The collected product was refluxed for 20 min to eliminate any residual hydrochloric acid. Finally the product was distilled at normal pressure. Yield: 280 g. Boiling point: 72°-74° C.

후처리

  1. customIn a three-necked 2 l flask provided with a Vigreux column, a condenser, and a collecting flask
  2. distillationdistilled over slowly
  3. temperatureThe collected product was refluxed for 20 min
  4. distillationFinally the product was distilled at normal pressure

출처 및 근거

ORD 기록
ord-c436943872e143dca8a6cbf920ea371e
출처 데이터셋
uspto-grants-1982_07
특허 번호
US04341864

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