6-Ethylchrysene → 12-Ethyl-6-chrysenecarbaldehyde

HRID 1762008

반응식

HRID 1762008 반응식
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:14](=[C:15]3[C:20]=1[CH:19]=[CH:18][CH:17]=[CH:16]3)[CH:13]=[CH:12][C:11]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]2=1)[CH3:2].C1C2C=CC3C(=CC([CH:39]=[O:40])=C4C=3C=CC=C4)C=2C=CC=1>C(Cl)Cl>[CH2:1]([C:3]1[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:5](=[C:6]3[C:11](=[C:12]([CH:39]=[O:40])[CH:13]=2)[CH:10]=[CH:9][CH:8]=[CH:7]3)[CH:4]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 759516-EthylchryseneHCID 124387746-Chrysenecarbaldehyde

생성물 1

HCID 1337539012-Ethyl-6-chrysenecarbaldehyde수율 76%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

6-Ethylchrysene (Cambridge Chemical, Inc., 60 g, 0.234 mol) was formylated according to the procedure outlined in 1A, except that CH2Cl2 ( 1 L) was used as the reaction solvent. The crude material was chromatographed on a plug of SiO2 (1 kg) using PhCH3 as the eluting solvent, afforded 50.38 g (76%) of 12-ethyl-6-chrysenecarbaldehyde mp 138°-139°, (C,H).

후처리

  1. customThe crude material was chromatographed on a plug of SiO2 (1 kg)

출처 및 근거

ORD 기록
ord-408512b0db114ddc98def94b327038ee
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04829090

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