1-Propanol → propyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 1762696노트

반응식

HRID 1762696 반응식
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[Na].[CH2:19]([OH:22])[CH2:20][CH3:21]>>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:22][CH2:19][CH2:20][CH3:21])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 3

HCID 10311-PropanolHCID 5360545SodiumHCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

생성물 1

HCID 19833889propyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

실험 절차

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and sodium propylate in n-propanol there is obtained propyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate and therefrom with hydrochloric acid in alcohol there is obtained the hydrochloride, m.p. 147° C. (with decomposition);

출처 및 근거

ORD 기록
ord-a57298802da74af7ac3f795bbfb4f70e
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04833245

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