Isobutanol → isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

반응식

[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH2:18]([OH:22])[CH:19]([CH3:21])[CH3:20]>>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:22][CH2:18][CH:19]([CH3:21])[CH3:20])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

참가 물질

반응물 2

HCID 6560Isobutanol

HCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

생성물 1

HCID 20041728isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

실험 절차

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and isobutanol there is obtained isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate as a resinous product, 1H-NMR(CDCl3): 1.07 [d, CH(CH3)2 ], 2.1 (m, 1H), 3.95 (d, CH2), 4.25 (s, 4H), 4.55 (broad s, NH), 7.3-7.7 (8H);

출처 및 근거

ORD 기록: ord-5912f29b2edc4e4e9971c468a3c209b8
출처 데이터셋: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04833245

반응 노트

불러오는 중…