Homoallyl bromide → 4-Bromobutyldimethylchlorosilane

HRID 1762721

반응식

HRID 1762721 반응식
[Br:1][CH2:2][CH2:3][CH:4]=[CH2:5].[CH3:6][SiH:7]([CH3:9])[Cl:8]>CC(O)C.C1(C)C=CC=CC=1.O.Cl.Cl.Cl[Pt](Cl)(Cl)Cl>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][Si:7]([CH3:9])([CH3:6])[Cl:8]

참가 물질

6

반응물 2

HCID 21241Homoallyl bromideHCID 66108Chlorodimethylsilane

생성물 1

HCID 143834624-Bromobutyldimethylchlorosilane수율 75.7%

시약·촉매·용매 3

HCID 16211507Platinate(2-), hexachloro-, hydrogen, hydrate (1:2:1), (OC-6-11)-촉매HCID 1140Toluene용매HCID 3776Isopropanol용매

반응 조건

온도
60 °C

실험 절차

Hexachloroplatinic acid hexahydrate (0.02 g, 0.039 mmole) was dissolved in a minimum of 2-propanol. This solution was dissolved in 75 ml toluene under argon. 2-propanol and water were removed by azeotropically distilling 25 ml of the toluene. The resulting solution was stirred and 6.17 g (0.046 mole) of 4-bromo-1-butene was added at 40° C. 4.32 g (0.046 mole) of dimethylchlorosilane was slowly added and the solution was heated to 60° C. and allowed to react for four hours. The mixture was distilled to remove the toluene. Further vacuum distillation yielded 8.0 g of product with a b.p. of 92°-95° C. at 5 mm Hg pressure. 'H NMR confirmed the structure.

후처리

  1. custom2-propanol and water were removed
  2. distillationby azeotropically distilling 25 ml of the toluene
  3. customto react for four hours
  4. distillationThe mixture was distilled
  5. customto remove the toluene
  6. distillationFurther vacuum distillation

출처 및 근거

ORD 기록
ord-a15d1ae6b3414632a1b2c5cd706dd8db
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04833262

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