Iodoethane → Ethyl 2,6-bis(trifluoromethyl)-4-ethoxy-3-pyridinecarboxylate

반응식

[F:1][C:2]([F:20])([F:19])[C:3]1[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:7]([OH:14])[CH:6]=[C:5]([C:15]([F:18])([F:17])[F:16])[N:4]=1.[CH2:21](I)[CH3:22]>>[F:20][C:2]([F:19])([F:1])[C:3]1[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:7]([O:14][CH2:21][CH3:22])[CH:6]=[C:5]([C:15]([F:18])([F:17])[F:16])[N:4]=1

참가 물질

반응물 2

HCID 6340Iodoethane

HCID 178470034HCID 178470034, 화합물

생성물 1

HCID 13882869Ethyl 2,6-bis(trifluoromethyl)-4-ethoxy-3-pyridinecarboxylate수율 77%

실험 절차

This material was prepared following the procedure of Example 4 in 77% yield from product of Example 2 and ethyl iodide as a white solid; mp 57°-59° C.

후처리

customThis material was prepared

출처 및 근거

ORD 기록: ord-cb373a2625bc4b909a51a13a471e6a62
출처 데이터셋: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04835279

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