Sodium Hydroxide → HCID 20307400, 화합물

HRID 1763784

반응식

HRID 1763784 반응식
Br[CH2:2][CH:3]=[O:4].[CH3:5][CH:6]([NH2:12])[CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10].[OH-].[Na+]>O>[CH3:5][CH:6]([NH:12][CH2:2][CH:3]=[O:4])[CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10]

참가 물질

5

반응물 3

HCID 14798Sodium HydroxideHCID 342045-Methyl-2-hexylamineHCID 105131Acetaldehyde, bromo-

생성물 1

HCID 20307400HCID 20307400, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
100 °C

실험 절차

The diethylacetal of 2-bromoacetaldehyde (40 grams) and 1,4-dimethylpentylamine (50 grams) were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture was heated at a temperature of about 100° C. for a period of about 3 hours. After this time sodium hydroxide (10 grams) dissolved in water (100 ml) was added and the resulting mixture stirred for about 30 minutes. The reaction mixture was then extracted with ether. The ether extract was separated, dried over magnesium sulfate, filtered and stripped of solvent under reduced pressure to yield the desired product the diethylacetal of 2-(1,4-dimethylpentylamino)acetaldehyde having a boiling point of 95° C. at 1 mm of Hg pressure.

후처리

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. additionwas added
  4. extractionThe reaction mixture was then extracted with ether
  5. extractionThe ether extract
  6. customwas separated
  7. dry with materialdried over magnesium sulfate
  8. filtrationfiltered

출처 및 근거

ORD 기록
ord-dd0ee538c13e454d8bc039c1439d89ca
출처 데이터셋
uspto-grants-1978_09
특허 번호
US04113464

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