Hydrochloric Acid → HCID 20308866, 화합물

HRID 1763944노트

반응식

HRID 1763944 반응식
[NH2:1][C:2](=[O:29])[C:3]([NH:5][CH:6]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:7]([O:9]C(C1C=CC=CC=1)C1C=CC=CC=1)=[O:8])=[O:4].Cl>C(O)(=O)C>[NH2:1][C:2](=[O:29])[C:3]([NH:5][CH:6]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:7]([OH:9])=[O:8])=[O:4]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 86736018Diphenylmethyl α-[(2-amino-2-oxoacetyl)amino]benzeneacetate

생성물 1

HCID 20308866HCID 20308866, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

13 g. of the product of Example 12 are added to 250 ml. of a 6N solution of hydrochloric acid in glacial acetic acid. After stirring for 15 minutes everything dissolves. The reaction solution is evaporated at room temperature and the white crystalline residue is triturated with ether, filtered under suction and recrystallized from water to obtain DL-α-[(2-amino-1,2-dioxoethyl)amino]phenylacetic acid as white crystals, m.p. 193°.

후처리

  1. dissolutiondissolves
  2. customThe reaction solution is evaporated at room temperature
  3. customthe white crystalline residue is triturated with ether
  4. filtrationfiltered under suction
  5. customrecrystallized from water

출처 및 근거

ORD 기록
ord-000079a2dfc64037819f825beb8631fb
출처 데이터셋
uspto-grants-1978_09
특허 번호
US04113943

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