Hydrochloric Acid → 128668-80-4

HRID 1770132노트

반응식

HRID 1770132 반응식
C(O)C.Cl.[C:5]([N:13](C)[CH2:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([CH3:23])=[O:22])=[CH:17][CH:16]=1)(=O)C1C=CC=CC=1>O>[CH3:5][NH:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([CH3:23])=[O:22])=[CH:17][CH:16]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 20095449HCID 20095449, 화합물

생성물 1

HCID 12153283128668-80-4수율 84.1%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a mixture of ethanol (40 ml), water (20 ml) and conc. hydrochloric acid (60 ml), N-benzoyl-N-methyl-N-(4-methylsulfinylbenzyl)amine (4.1 g) is added and the mixture is heated with refluxing for 12 hours. After the reaction, the solvent is distilled off under reduced pressure, and to the resulting residue is added 20% aqueous sodium hydroxide solution, and the mixture is extracted with diethyl ether. The extract is washed successively with water and aqueous sodium chloride solution, and dried over magnesium sulfate. Diethyl ether is distilled off to give N-methyl-N-(4-methylsulfinylbenzyl)amine (2.2 g).

후처리

  1. additionis added
  2. temperaturethe mixture is heated
  3. temperaturewith refluxing for 12 hours
  4. customAfter the reaction
  5. distillationthe solvent is distilled off under reduced pressure
  6. additionto the resulting residue is added 20% aqueous sodium hydroxide solution
  7. extractionthe mixture is extracted with diethyl ether
  8. washThe extract is washed successively with water and aqueous sodium chloride solution
  9. dry with materialdried over magnesium sulfate
  10. distillationDiethyl ether is distilled off

출처 및 근거

ORD 기록
ord-88f063bbbccd406da7792317edaaaa16
출처 데이터셋
uspto-grants-1995_01
특허 번호
US05385914

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