N-bromobutanimide → Methyl 4-(Bromomethyl)-2-tert-butylthiazole-5-carboxylate
반응식
[Br:1]C1C(C)=C(NCC2C=C(C(C)(C)C)SC=2C(O)=O)C=CC=1.[CH3:23][C:24]1[N:25]=[C:26]([C:33]([CH3:36])([CH3:35])[CH3:34])[S:27][C:28]=1[C:29]([O:31][CH3:32])=[O:30].BrN1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:1][CH2:23][C:24]1[N:25]=[C:26]([C:33]([CH3:36])([CH3:35])[CH3:34])[S:27][C:28]=1[C:29]([O:31][CH3:32])=[O:30]참가 물질
5
반응물 3
생성물 1
시약·촉매·용매 1
실험 절차
Using the same general procedure as described for the preparation of 102e, reaction of methyl 4-methyl-2-tert-butylthiazole-5-carboxylate with N-bromo-succinimide in carbon tetrachloride afforded 125a.
출처 및 근거
- ORD 기록
- ord-bd38f8fb59d04dec882a49780967104f
- 출처 데이터셋
- uspto-grants-2016_02
- 특허 번호
- US09249123B2
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