Trimethoxysilane → N,N-dimethyl-2-(3-(trimethoxysilyl)propoxy)ethanamine

HRID 1772583노트

반응식

HRID 1772583 반응식
[CH2:1]([O:4][CH2:5][CH2:6][N:7]([CH3:9])[CH3:8])[CH:2]=[CH2:3].[CH3:10][O:11][SiH:12]([O:15][CH3:16])[O:13][CH3:14]>C([Si](C)(C)O[Si](C=C)(C)C)=C.[Pt].C1(C)C=CC=CC=1>[CH3:8][N:7]([CH3:9])[CH2:6][CH2:5][O:4][CH2:1][CH2:2][CH2:3][Si:12]([O:15][CH3:16])([O:13][CH3:14])[O:11][CH3:10]

참가 물질

5

반응물 2

HCID 17215TrimethoxysilaneHCID 261277n,n-Dimethyl-2-(prop-2-en-1-yloxy)ethanamine

생성물 1

HCID 86713993N,N-dimethyl-2-(3-(trimethoxysilyl)propoxy)ethanamine수율 86%

시약·촉매·용매 2

HCID 10959889Platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane촉매HCID 1140Toluene용매

실험 절차

After adding toluene (200 mL) to a round-bottom flask containing 2-(allyloxy)-N,N-dimethylethanamine (0.398 mol) and dissolving trimethoxysilane (0.398 mol), a commercially available platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane solution was added and the mixture was stirred for 24 hours. Upon completion of reaction, after removing the solvent through distillation under reduced pressure, 0.342 mol (yield: 86%) of the target compound was obtained by extracting with water and diethyl ether. 1H and 13C NMR spectroscopic data of the purified N,N-dimethyl-2-(3-(trimethoxysilyl)propoxy)ethanamine are as follows.

후처리

  1. customUpon completion of reaction
  2. customafter removing the solvent
  3. distillationthrough distillation under reduced pressure

출처 및 근거

ORD 기록
ord-c7d3a48db84e4f808a64d1cf43fca7b7
출처 데이터셋
uspto-grants-2016_02
특허 번호
US09249276B2

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