Trimethylsilylacetylene → 3-trifluoromethyl-5-(4-methylimidazol-1-yl)-N-[3-(2-(5-trifluoromethyl-1H-imidazol-2-yl)pyridin-5-yl)ethynyl-4-fluorophenyl]-benzamide

반응식

[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([N:12]2[CH:16]=[C:15]([CH3:17])[N:14]=[CH:13]2)[CH:11]=1)[C:6](Cl)=[O:7].I[C:21]1[CH:22]=[C:23]([CH:25]=[CH:26][C:27]=1[F:28])[NH2:24].C[Si]([C:33]#[CH:34])(C)C.[F:35][C:36]([F:50])([F:49])[C:37]1[NH:41][C:40]([C:42]2[CH:47]=[CH:46][C:45](Br)=[CH:44][N:43]=2)=[N:39][CH:38]=1>>[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([N:12]2[CH:16]=[C:15]([CH3:17])[N:14]=[CH:13]2)[CH:11]=1)[C:6]([NH:24][C:23]1[CH:25]=[CH:26][C:27]([F:28])=[C:21]([C:33]#[C:34][C:45]2[CH:46]=[CH:47][C:42]([C:40]3[NH:41][C:37]([C:36]([F:50])([F:49])[F:35])=[CH:38][N:39]=3)=[N:43][CH:44]=2)[CH:22]=1)=[O:7]