Hydrochloric Acid → 6-(4-Amino-2-fluorophenoxy)-N-(4-(benzyloxy)phenyl)pyrimidin-4-amine

반응식

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:33])[cH:25][c:26]([NH:29][C:30](=[O:31])[CH3:32])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1.[CH3:35][OH:36].[ClH:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:33])[cH:25][c:26]([NH2:29])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 59852842N-(4-(6-(4-(benzyloxy)phenylamino)pyrimidin-4-yloxy)-3-fluorophenyl)acetamide

생성물 1

HCID 598530036-(4-Amino-2-fluorophenoxy)-N-(4-(benzyloxy)phenyl)pyrimidin-4-amine

출처 및 근거

ORD 기록: ord-1ae57370315f475fa0da5ffa69f86616
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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