Water → HCID 178419284, 화합물
반응식
[Br:1][C:2]1[CH:3]=[C:4]2[CH:10]=[N:9][NH:8][C:5]2=[CH:6][N:7]=1.C1C(=O)N([I:18])C(=O)C1.O>CN(C=O)C>[Br:1][C:2]1[CH:3]=[C:4]2[C:10]([I:18])=[N:9][NH:8][C:5]2=[CH:6][N:7]=1참가 물질
5
실험 절차
A solution containing 5-bromo-1H-pyrazolo[3,4-c]pyridine (168.0 g, 848.4 mmol) and NIS (286.3 g, 1.27 mol) in DMF (1.2 L) was stirred on at room temperature. The reaction mixture was poured into water then filtered. The solid was washed with water and 5% Na2S2O5. The crude product was dried under high vacuum overnight to give 5-bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine.
후처리
- filtrationthen filtered
- washThe solid was washed with water and 5% Na2S2O5
- dry with materialThe crude product was dried under high vacuum overnight
출처 및 근거
- ORD 기록
- ord-849bcbca85004f7cad2bcf9fa1ac2de1
- 출처 데이터셋
- uspto-grants-2016_02
- 특허 번호
- US09260425B2
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