Acetic Anhydride → HCID 11041076, 화합물

HRID 1779707노트

반응식

[CH3:1][CH:2]([C:7](=[O:13])[CH2:8][CH2:9][C:10]([CH3:12])=[CH2:11])[CH2:3][C:4]([OH:6])=O.C(OC(=O)C)(=O)C>>[CH3:1][C:2]1[CH:7]([CH2:8][CH:9]=[C:10]([CH3:11])[CH3:12])[O:13][C:4](=[O:6])[CH:3]=1

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 110195357-Octenoic acid, 3,7-dimethyl-4-oxo-

생성물 1

HCID 11041076HCID 11041076, 화합물

실험 절차

The thus-obtained 3,7-dimethyl-4-oxo-7-octenoic acid is then dissolved in a solvent and an equivalent amount or a somewhat excessive amount of acetic anhydride is added thereto and heated under reflux in the presence of an acid catalyst, whereby the acid is cyclized and dehydrated along with isomerization of the terminal double bond to give 3,7-dimethyl-2,6-octadien-4-olide. As the solvent in this process, usable is a hydrocarbon solvent such as pentane, hexane, heptane, benzene, toluene, xylene or the like. Especially preferred is toluene. As the acid catalyst, usable is an organic acid such as acetic acid, para-toluene-sulfonic acid, camphor-sulfonic acid or the like.

후처리

temperatureheated
temperatureunder reflux in the presence of an acid catalyst, whereby the acid

출처 및 근거

ORD 기록: ord-252282c9a713493783db2779cb37c19f
출처 데이터셋: uspto-grants-1997_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05627288

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