Hydrochloric Acid → 2-[4-(Aminomethyl)phenyl]ethan-1-ol

HRID 1781392노트

반응식

HRID 1781392 반응식
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8][OH:9])=[CH:5][CH:4]=1)#[N:2].Cl>C(O)C.[Pd]>[OH:9][CH2:8][CH2:7][C:6]1[CH:10]=[CH:11][C:3]([CH2:1][NH2:2])=[CH:4][CH:5]=1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 28008154-(2-Hydroxyethyl)benzonitrile

생성물 1

HCID 226014582-[4-(Aminomethyl)phenyl]ethan-1-ol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 0.74 g (0.005 mol) of p-cyanophenethyl alcohol in 50 ml of ethanol containing 10 ml of concentrated hydrochloric acid was hydrogenated at 30 psi using 0.1 g 5% Pd/C for 72 hours. The catalyst was removed by filtration and the solvent was removed under reduced pressure.

후처리

  1. customfor 72 hours
  2. customThe catalyst was removed by filtration
  3. customthe solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-318a0d649152403aa70213f1e775d186
출처 데이터셋
uspto-grants-1997_05
특허 번호
US05633247

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