Sodium Hydroxide → HCID 178518972, 화합물

HRID 1781617노트

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HRID 1781617 반응식
[OH-:1].[Na+].[Cl:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]1[C:14](Cl)=[N:13][N:12]=[N:11]1>O>[CH:7]1[CH:6]=[C:5]([N:10]2[NH:11][N:12]=[N:13][C:14]2=[O:1])[C:4]([Cl:3])=[CH:9][CH:8]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 153465581-(2-Chloro-phenyl)-5-chlorotetrazole

생성물 1

HCID 178518972HCID 178518972, 화합물수율 96%

시약·촉매·용매 1

HCID 962Water용매3회

반응 조건

온도
110 °C

실험 절차

A solution of sodium hydroxide (13 g, about 45% by weight) in water, 1-(2-chloro-phenyl)-5-chlorotetrazole (12.9 g) in water (6.5 ml) were mixed and the mixture was heated to 110° C. The reaction was initiated and the temperature increased to 115° C. After 3 minutes from the initiation of the reaction, the temperature was lowered to room temperature and then water (20 ml) was added. The insoluble matter was extracted with toluene (10 ml) and the aqueous solution was adjusted to a pH of 1. The solid matter was collected by filtration followed by washing with water and drying to obtain a pale tan solid 1-(2-chlorophenyl)-5(4H)-tetrazolinone (11.3 g) (yield: 96%). melting point: 123°-125° C.

후처리

  1. temperaturethe temperature increased to 115° C
  2. customAfter 3 minutes from the initiation of the reaction
  3. customwas lowered to room temperature
  4. extractionThe insoluble matter was extracted with toluene (10 ml)
  5. filtrationThe solid matter was collected by filtration
  6. washby washing with water
  7. customdrying

출처 및 근거

ORD 기록
ord-a71703d6b6b4447d8aef3942b26b3745
출처 데이터셋
uspto-grants-1997_05
특허 번호
US05633387

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