2-Chlorobenzylamine → HCID 178516939, 화합물

반응식

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH2:5].[S:10]1[CH2:16][C:14](=[O:15])[NH:13][C:11]1=S.CCN(C(C)C)C(C)C>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH:5][C:11]1[S:10][CH2:16][C:14](=[O:15])[N:13]=1

참가 물질

반응물 3

HCID 666482-Chlorobenzylamine

HCID 81531Diisopropylethylamine

HCID 1201546Rhodanine

생성물 1

HCID 178516939HCID 178516939, 화합물

실험 절차

Similar procedure as described in example 10c was used, starting with 2-chloro-benzylamine, rhodanine, mercuric chloride and DIEA to give 2-(2-chloro-benzylamino)-thiazol-4-one. LC-MS m/e 241 (MH+).

출처 및 근거

ORD 기록: ord-160243ad90a7412693e3a5dd49a9d7f0
출처 데이터셋: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07501428B2

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