Diisopropylethylamine → HCID 178516941, 화합물

HRID 1783639노트

반응식

HRID 1783639 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[F:10])[CH2:5][NH2:6].[S:11]1[CH2:17][C:15](=[O:16])[NH:14][C:12]1=S.CCN(C(C)C)C(C)C>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[F:10])[CH2:5][NH:6][C:12]1[S:11][CH2:17][C:15](=[O:16])[N:14]=1

참가 물질

4

반응물 3

HCID 81531DiisopropylethylamineHCID 1445393-Chloro-4-fluorobenzylamineHCID 1201546Rhodanine

생성물 1

HCID 178516941HCID 178516941, 화합물

실험 절차

Similar procedure as described in example 15a was used, starting with 3-chloro-4-fluoro-benzylamine, rhodanine, mercuric chloride and DIEA to give 2-(3-chloro-4-fluoro-benzylamino)-thiazol-4-one. LC-MS m/e 259 (MH+).

출처 및 근거

ORD 기록
ord-26ca6e323b3c47bda99c583f50a3b29a
출처 데이터셋
uspto-grants-2009_03
특허 번호
US07501428B2

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