Acetonitrile → 1-(4-Bromo-phenyl)-6-methoxy-3,4-dihydro-isoquinoline

반응식

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][CH2:10][c:11]2[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]2)[cH:19][cH:20]1.[CH3:26][C:27]#[N:28].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:6]2=[N:8][CH2:9][CH2:10][c:11]3[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][c:16]32)[cH:19][cH:20]1

참가 물질

반응물 3

HCID 6342Acetonitrile

HCID 24813Phosphorus oxychloride

HCID 110241034-bromo-N-[2-(3-methoxyphenyl)ethyl]benzamide

생성물 1

HCID 118232271-(4-Bromo-phenyl)-6-methoxy-3,4-dihydro-isoquinoline

출처 및 근거

ORD 기록: ord-fd853c9f7aa248f9880026f99e1cffa2
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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