Hydrochloric Acid → 7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3,4-dihydroisoquinoline-2(1H)-carboxamide

HRID 178795

반응식

HRID 178795 반응식
[CH3:18][N:19]1[CH2:20][CH2:21][N:22]([c:25]2[n:26][c:27]([NH2:41])[n:28][c:29](-[c:31]3[cH:32][cH:33][c:34]4[c:39]([cH:40]3)[CH2:38][NH:37][CH2:36][CH2:35]4)[cH:30]2)[CH2:23][CH2:24]1.[Cl:14][C:15]([Cl:16])=[O:17].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH2:13])[s:11][cH:12]2)[cH:6][cH:7]1.[ClH:42]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH:13][C:15](=[O:17])[N:37]3[CH2:36][CH2:35][c:34]4[cH:33][cH:32][c:31](-[c:29]5[n:28][c:27]([NH2:41])[n:26][c:25]([N:22]6[CH2:21][CH2:20][N:19]([CH3:18])[CH2:24][CH2:23]6)[cH:30]5)[cH:40][c:39]4[CH2:38]3)[s:11][cH:12]2)[cH:6][cH:7]1

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 6371PhosgeneHCID 732412-Amino-4-(4-chlorophenyl)thiazoleHCID 497794384-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine

생성물 1

HCID 594966377-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3,4-dihydroisoquinoline-2(1H)-carboxamide

출처 및 근거

ORD 기록
ord-5d5d343915204531a8a09fad09e84886
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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