3-Dimethoxymethyl-4-nitro-benzoic Acid Methyl Ester → 3-Dimethoxymethyl-4-nitro-benzoic Acid
반응식
C[O:2][C:3](=[O:18])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[C:6]([CH:13]([O:16][CH3:17])[O:14][CH3:15])[CH:5]=1>CO.[OH-].[Na+]>[CH3:17][O:16][CH:13]([O:14][CH3:15])[C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][C:7]=1[N+:10]([O-:12])=[O:11])[C:3]([OH:18])=[O:2]참가 물질
4
실험 절차
To a solution of 5.49 g (21.5 mmol) of Compound 5 in 200 mL of methanol, 50 mL of 1M NaOH were added and the mixture was stirred at room temperature for 2 h. The reaction mixture was then evaporated to dryness, the residue was dissolved in 100 mL water, acidified with 1 M HCl to pH 3-4. The precipitate was then filtered off, washed with water (4×), and dried. Yield: 4.96 g (95%).
후처리
- customThe reaction mixture was then evaporated to dryness
- dissolutionthe residue was dissolved in 100 mL water
- filtrationThe precipitate was then filtered off
- washwashed with water (4×)
- customdried
출처 및 근거
- ORD 기록
- ord-28d046793373421aa5344a8501d964e6
- 출처 데이터셋
- uspto-grants-2009_03
- 특허 번호
- US07511145B2
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