Indoline → HCID 59909605, 화합물

HRID 1790427

반응식

HRID 1790427 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[C:10]([N:13]1[CH2:18][CH2:17][C:16](=O)[CH:15]([C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH2:14]1)(=[O:12])[CH3:11]>>[C:10]([N:13]1[CH2:18][CH2:17][C@H:16]([N:1]2[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[CH2:3][CH2:2]2)[C@H:15]([C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH2:14]1)(=[O:12])[CH3:11]

참가 물질

3

반응물 2

HCID 10328IndolineHCID 12445847Ethyl 1-acetyl-4-oxo-3-piperidinecarboxylate

생성물 1

HCID 59909605HCID 59909605, 화합물수율 22%

실험 절차

Indoline (12.5 g), ethyl 1-acetyl-4-oxo-3-piperidinecarboxylate (22.3 g) and triacetoxylated sodium borohydride (48.7 g) were treated as in Example 1 to give the title compound (7.12 g) as a pale yellow powder (yield: 22%).

출처 및 근거

ORD 기록
ord-feb2337b8d0f47378f7cf0a77a12479f
출처 데이터셋
uspto-grants-2006_07
특허 번호
US07071201B2

연결된 노트

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