Hydrochloric Acid → 2-(1h-Pyrazol-3-yl)-benzylamine hydrochloride salt

HRID 1795279노트

반응식

HRID 1795279 반응식
[ClH:1].[NH:2]1[CH:6]=[CH:5][C:4]([C:7]2[CH:21]=[CH:20][CH:19]=[CH:18][C:8]=2[CH2:9][NH:10]C(=O)OC(C)(C)C)=[N:3]1>C(OCC)(=O)C>[ClH:1].[NH:2]1[CH:6]=[CH:5][C:4]([C:7]2[CH:21]=[CH:20][CH:19]=[CH:18][C:8]=2[CH2:9][NH2:10])=[N:3]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 178453037HCID 178453037, 화합물

생성물 1

HCID 1784791782-(1h-Pyrazol-3-yl)-benzylamine hydrochloride salt

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

hydrogen chloride gas was bubbled through a 0° C. solution of tert-butyl 2-(1H-pyrazol-3-yl)benzylcarbamate (60 mg, 0.220 mmol) in ethyl acetate (5 ml) for 2 min and stirred for 40 min. A precipitate formed, and the suspension was concentrated in vacuo to give 2-(1H-pyrazol-3-yl)-benzylamine hydrochloride salt; MS (ES+) M+1 174.1 for C10H11N3.

후처리

  1. customA precipitate formed
  2. concentrationthe suspension was concentrated in vacuo

출처 및 근거

ORD 기록
ord-4b9e7267a4a74d259bccad4c8bb88b5c
출처 데이터셋
uspto-grants-2006_04
특허 번호
US07026324B2

반응 노트

불러오는 중…