Benzil → Hydrobenzoin

HRID 1796957

반응식

HRID 1796957 반응식
[C:1]1([C:7]([C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:10])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[BH4-].[Na+]>CCO.O>[C:11]1([CH:9]([CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[OH:8])[OH:10])[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

참가 물질

5

반응물 2

HCID 8651BenzilHCID 4311764Sodium borohydride

생성물 1

HCID 95447Hydrobenzoin

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

반응 조건

온도
2.5 °C

실험 절차

To a slurry of 97.0 g of benzil in 1 liter of 95% EtOH was added 20 g of sodium borohydride. After stirring 10 minutes, the mixture was diluted with 1 liter of water and the mixture was treated with activated carbon. The mixture was then filtered trough supercel and the filtrate heated and diluted with an additional 2 liters of water until it became slightly cloudy. The mixture was then cooled to 0 to 5° C. and the resulting crytals were collected and washed with cold water. The crystals were then dried in vacuo.

후처리

  1. additionthe mixture was treated with activated carbon
  2. filtrationThe mixture was then filtered trough supercel
  3. temperaturethe filtrate heated
  4. additiondiluted with an additional 2 liters of water until it
  5. customthe resulting crytals were collected
  6. washwashed with cold water
  7. customThe crystals were then dried in vacuo

출처 및 근거

ORD 기록
ord-7f1fdae056914c53929bc0162e0ff096
출처 데이터셋
uspto-grants-2006_04
특허 번호
US07034026B2

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