Thionyl Chloride → 2-(Chloromethyl)-4H-1-benzopyran-4-one

HRID 1801698노트

반응식

HRID 1801698 반응식
O[CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.S(Cl)([Cl:16])=O>C(Cl)(Cl)Cl>[Cl:16][CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 12536095HCID 12536095, 화합물

생성물 1

HCID 140019552-(Chloromethyl)-4H-1-benzopyran-4-one

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

The 2-(hydroxymethyl)-4H-chromen-4-one was dissolved in 30 ml of anhydrous chloroform at room temperature, 1 ml of thionyl chloride was added to the solution, and reaction mixture was stirred at room temperature for 24 hours. The solvent was thereafter evaporated, and the obtained liquid was dissolved in anhydrous hexane, which was also evaporated again to give 2-(chloromethyl)-4H-chromen-4-one which was further reacted without purification.

후처리

  1. customThe solvent was thereafter evaporated
  2. dissolutionthe obtained liquid was dissolved in anhydrous hexane
  3. customwhich was also evaporated again

출처 및 근거

ORD 기록
ord-b5905400d7834c8f8da2c7f4396fe488
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08349850B2

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