Hydrochloric Acid → (3-Aminomethyl-phenyl)-(2-morpholin-4-yl-ethyl)-amine hydrochloride

HRID 1803582노트

반응식

HRID 1803582 반응식
C(OC(=O)[NH:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([NH:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH:9]=1)(C)C.[ClH:24]>CO>[ClH:24].[NH2:6][CH2:7][C:8]1[CH:9]=[C:10]([NH:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH:11]=[CH:12][CH:13]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 67415913[3-(2-Morpholin-4-yl-ethylamino)-benzyl]-carbamic acid isopropyl ester

생성물 1

HCID 67416818(3-Aminomethyl-phenyl)-(2-morpholin-4-yl-ethyl)-amine hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of [3-(2-morpholin-4-yl-ethylamino)-benzyl]-carbamic acid isopropyl ester (200 mg, 0.596 mmol), methanol (4 mL) and 4.89N isopropanolic hydrochloric acid (2.4 mL) was stirred at room temperature overnight. The reaction was concentrated and dried to yield (3-aminomethyl-phenyl)-(2-morpholin-4-yl-ethyl)-amine hydrochloride (212 mg) as an orange solid. m/z (M+1) 236.04.

후처리

  1. concentrationThe reaction was concentrated
  2. customdried

출처 및 근거

ORD 기록
ord-c07357f643a14b7cb2763d6e7d3c9ebf
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08349836B2

반응 노트

불러오는 중…