Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-4-Methyloxazolidin-2-one → (R)-3-{5-[4-(4-chlorobenzoyl)piperidine-1-carbonyl]pyridin-2-yl}-4-methyloxazolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-4-Methyloxazolidin-2-one | HCID 2734858 | — |
| 반응물 | (6-Bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone | HCID 58484839 | — |
| 생성물 | (R)-3-{5-[4-(4-chlorobenzoyl)piperidine-1-carbonyl]pyridin-2-yl}-4-methyloxazolidin-2-one | HCID 54755117 | 41.8% |
반응 단계
By reaction and treatment in the same manner as in Preparation Example 31 and using (6-bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone (2 g) described in Preparation Example 23 and (R)-4-methyloxazolidin-2-one (288 mg) described in Preparation Example 25, the title compound (510 mg) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08354401B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-d93e8706497c4c05b6903add2c842b7b |
| 출처 메모 | uspto-grants-2013_01 |