Methyl iodide → 1,4-Dimethylpyridinium Iodide

HRID 1808279노트

반응식

HRID 1808279 반응식
[N:1]1[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][CH:2]=1.[CH3:8][I:9]>C1(C)C=CC=CC=1>[I-:9].[CH3:8][N+:1]1[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 79634-Methylpyridine

생성물 1

HCID 2006031,4-Dimethylpyridinium Iodide수율 67.2%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a solution of 4-picoline (18.6 g, 0.2 mol) in toluene (100 mL), methyl iodide (56.8 g, 0.4 mol) was added dropwise at room temperature. After the addition, the mixture was stirred at room temperature for 5 hrs. The precipitate was collected by filtration, washed with toluene and dried under vacuum to give Compound 7 as an off-white solid (31.6 g, 67%). The structure of Compound 7 is given below:

후처리

  1. additionAfter the addition
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with toluene
  4. customdried under vacuum

출처 및 근거

ORD 기록
ord-0920f8afa7de4fbc89f0a13f8b034f49
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08357801B2

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